Haplotype-specific identification of genetic and epigenetic variation using nanopore sequencing

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Haplotype-specific identification of genetic and epigenetic variation using nanopore sequencing
Bases

It takes two — haplotype-specific identification of genetic and epigenetic variation using nanopore sequencing

Using nanopore sequencing, researchers can achieve real-time, high-performance, accessible, and scalable analysis of DNA and RNA, with the added benefits of high-accuracy variant discovery, built-in methylation detection, and so much more.

To learn more, listen to Philipp Rescheneder discuss assigning variants to the correct haplotype through phasing, and how nanopore sequencing can improve the understanding of tumour development.

Register here

methylation

A guide to investigating methylation in the human genome

This guide provides an introduction to the direct sequencing of DNA methylation in human genomes – from designing your protocol, all the way through to analysing your data.

Download guide

DNA Methylation

Methylation detection with nanopore sequencing

Our recent Knowledge Exchanges introduce Remora, for genome-wide methylation detection, and Reduced-Representation Methylation Sequencing, for targeted methylation detection.

Watch here

Fully characterise human genetic variation with real-time nanopore sequencing technology

With nanopore technology, there is no limit to read length (current record >4 Mb), enabling complete resolution of challenging regions and uncovering previously hidden variation. Plus, you can identify base modifications as standard, with amplification-free native DNA or RNA sequencing.

Learn more

 

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