Detect Fluid Biomarkers in Neurodegeneration

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Quantify Mediators of Inflammation with Highly Sensitive ELISA


Activated microglia are one of the early hallmarks of Alzheimer's disease (AD) pathogenesis. Both amyloid beta (Aβ) and tau trigger a cascade of functional changes in neurons, microglia, astrocytes, and oligodendrocytes, which results in neuronal dysfunction, synaptic loss, innate immune system activation, inflammation, and neurodegeneration.

Cytokines play a central role in controlling inflammation and contributing to the balance between immune activation and suppression. Enzo offers hundreds of ultrasensitive, time-saving, and widely cited ELISA kits to measure pro- (IL-1, IL-6, TNF-α, IL-12) and anti-inflammatory factors (IL-4, IL-10) in neurodegenerative diseases.

Pair Enzo's new plate reader with any of our 250 ELISAs cited in more than 200 publications, including the amyloid precursor protein APP ΔC31 ELISA kit. Learn how Poksay et al. used Enzo's APP ΔC31 ELISA kit in their study.


Are you doing neuroscience research? Enzo's 40 years of expertise across research disciplines including neuroscience, antibodies and immunoassays development, provides a unique collection of scientific tools to advance neuroscience research. Ask a Scientist today.
 

Trusted Tools for Neuroscience Research
Backed by Hundreds of Citations

 
 

Efficient and Accurate Results with 200+ Rapid ELISAs and new Compact Plate Reader

Absorbance 96 Plate Reader Virtual Demonstration

Do you want to see how easy-to-use and efficient the Absorbance 96 is?

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Explore our ELISA kits for your neurodegenerative research

APP ΔC31 ELISA kit



Inhibition experiment by ELISA and Western blot analysis indicates both methods are in agreement using treatment of increasing concentrations of caspase inhibitor which reduces the production of APP ΔC31.

CRP (human) ELISA kit



The CRP (human) ELISA kit is a complete, colorimetric, competitive immunoassay kit for the quantitative determination of human CRP in serum and plasma with results in 3 hours.

24(S)-Hydroxycholesterol ELISA kit



24-OHC levels in supernatants of cells transfected with catalytically active or mutant (mut) CYP46A1.



Application Note

A Colorimetric ELISA Enabling Quantification of APP Δ C31 in Cell Lysates and Cerebrospinal Fluid
 



Literature


Essential Research Tools for Neurodegeneration & Neural Signaling
 


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Absorbance 96 - A Personal, Compact Plate Reader
 


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