Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.
In cases where conventional drugs are insufficient, PROTACs can inactivate targets by bringing them into contact with protein degraders. In this case study from Synthego, learn how a researcher used a CRISPR knockout cell pool to validate a protein degrader's mechanism of action.
Using a novel software module, researchers quantify cell viability from microscopy images without needing fluorescent labels. Learn more in this article from Sartorius.
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